The aim of this study was to investigate the relationship between fatigue of temporomandibular joint (TMJ), neck disability and headache in individuals who were seperated into different groups according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). A total of 77 subjects with TMD participated in the study. Individuals were divided into 3 groups according to the RDC/TMD; group 1: Muscle disorders (n=25), group 2: Disc displacement (n=27), group 3: Other joint diseases (n=25). After obtaining the sociodemographic information of individuals; fatigue of TMJ with the gum chewing test, neck disability with the Copenhagen Neck Functional Disability Scale (CNFDS), and headache with the Headache Impact Test (HIT-6) were assessed. In the correlation analysis of individuals with TMD; the significant low correlation among parameters. When the current study and literature are investigated, there is a need for further research with high level of evidence.